GENTAPYX Gentamicin Injection B.P. 80mg/2m
Composition of GENTAPYX Gentamicin Injection B.P. 80mg/2m
Each 2m1. contains: Gentamicin Sulphate B.P. to Gentamicin 80 mg.
Water for Injection B.P. q.s.
Read all of this leaflet carefully before you start using this medicine.
Keep this leaflet. You may need to read it again.
If you have any further questions, ask your doctor or pharmacist.
If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor.
1. WHAT GENTAMICIN INJECTION IS AND WHAT IT IS USED FOR
Gentamicin Injection is an aminoglycoside antibiotic medicine, in the form of a solution for injection (a solution which can be given as an injection).
Gentamicin Injection is used to treat a wide variety of infections such as chest, wound and blood infections.
2. BEFORE YOU USE GENTAMICIN INJECTION
Do not use Gentamicin Injection
- if you have shown signs of hypersensitivity (severe allergy) to
- if you suffer from a disorder called myasthenia gravis (severe weakness of selected muscles of the body) and if you are pregnant or breast-feeding
Take special care with Gentamicin Injection
- if treating premature babies, and elderly patients, kidneys are not working properly
- if you have diabetes, an ear, or hearing disorder
- if you experience muscle weakness or are very overweight
Taking/using other medicines
Special care is needed if you are taking/using other medicines such as:
- antibiotics that also affect your kidneys or hearing, anticoagulant, amphotericin B, cyclosporine, neostigmine and pyridostigmine, cisplatin, some diuretics (water tablets), such as ethacrynic acid and furosemide, muscle relaxants, indomethacin, biphosphonates Botulinum Toxin etc. Please tell your doctor if you are taking or have recently taken any other medicines. Pregnancy and breast-feeding
Gentamicin Injection will not normally be used if you are pregnant or breastfeeding.
Driving and using machines
Do not drive if you experience any effect which may impair your ability to drive or use machines.
3. HOW TO USE GENTAMICIN INJECTION
The dose of medicine given to you will depend on how serious the infection is, your age, body weight and how well your kidneys are working.
The medicine is usually injected into a muscle but may also be injected into a vein in some patients.
If it is given into a vein, it can either be given as an injection or dissolved with, e.g. saline or 5% glucose in water and given as a slow injection via a drip (infusion).
4. POSSIBLE SIDE-EFFECTS
Like all medicines, Gentamicin Injection can cause side effects, although not everybody gets them. If any of the following happen, please tell your doctor immediately
- severe allergic reaction – you may experience a sudden itchy rash (hives), swelling of the hands, feet, ankles, face, lips, mouth or throat (which may cause difficulty in swallowing or breathing), and you may feel you are going to faint.
This is a very serious side-effect. You may need urgent medical attention. This very serious side effect is rare.
If you experience any of the following tell your doctor as soon as possible:
- hearing problems (if you have this side-effect your doctor may need to change your dose or give you other treatments)
- irreversible hearing loss, deafness
- feeling or being sick, (nausea or vomiting)
- skin rash or development of raised colored blotches which may be itchy
- Purple discoloration under the skin
- fever
- sore throat and mouth
- muscle weakness
- kidney disease with symptoms such as reduced urine output
- acute kidney failure
- low blood cell counts (red and white blood cells) and further blood abnormalities or disorders (known as blood dyscrasia) damage to the brain with signs such as seizures, confusion, tiredness, depression, and hallucinations
- liver problems
- low potassium or calcium levels in the blood
- low magnesium levels in the blood with prolonged treatment
- high urine levels of phosphate and amino acids (so-called Fanconi-like syndrome, associated with high doses given over a long time)
Your doctor may also regularly carry out blood tests to check for changes in your blood cells, electrolytes (such as potassium, calcium, and magnesium) in your blood, kidney, and liver function, as well as hearing tests.
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet..
5. HOW TO STORE GENTAMICIN INJECTION
Keep out of sight and reach of children.
Do not use Gentamicin Injection after the expiry date printed on the vial label and carton. The expiry date refers to the last day of that month.
The vials should not be stored above 25°C.
Marketed by:
PYXUS PHARMACEUTICALS PVT. LTD.
